Bulk Drugs
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Description |
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Colourless Aromatic Liquid having a stong, persistent and characteristic Odour.
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C8H8O3
(M.W. 152.15)) |
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Purity (Content of Methyl Salicylate) |
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Minimum 99.7% |
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Impurities |
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Extremely low heavy metals and phenol. |
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Solubility
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Complete and clear (1:7 ml of 70% Ethanol) |
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|
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1.535 to 1.538 |
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Specific Gravity
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1.180 to 1.185 |
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Acidity
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0.5 mgKOH/g maximum |
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Uses |
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As a flavouring agent in toothpastes, toothpowders, food products, mouthwashes,
oral care products
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Description |
: |
Colourless Aromatic Liquid having a stong, persistent and characteristic Odour.
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C8H8O3
(M.W. 152.15)) |
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Purity (Content of Methyl Salicylate) |
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Minimum 99% |
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Solubility
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Complete and clear (1:7 ml of 70% Ethanol) |
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Refractive Index
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1.535 to 1.538 |
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Specific Gravity
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1.180 to 1.185 |
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Acidity
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0.5 mgKOH/g maximum |
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Uses |
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In all pain balms and analgesic ointments. Also used to mask undesireable odours
etc. |
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Chemical Name
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O-Hydroxy Benzamide |
C7H7NO2
(M.W. 137.14)) |
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Technical Information
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White or slightly pink crystalline powder. Bitter in taste, sensation of warmth
on tongue, forms water soluble Sodium Salt at 9pH.
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Description |
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A colourless crystalline powder. |
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Odour |
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Almost Odourless. |
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Melting Range
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139oC - 142oC. |
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Solubility
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Soluble in hot water, chloroform and ether.
pH of saturated aqueous solution at 25oC is 5.0.Solubility in water at 30oC is 0.2%
at 47oC is 0.8%; Solubility in Glycerol at 5oC is 2.0%; at 39oC is 5%; at 60oC is
10%. Solubility in Propylene Glycol at 5oC is 10%.
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Infra red absorption |
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Passes test. |
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Ultraviolet absorption |
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Passes test. |
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Water |
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0.5% (max). |
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Residue on ignition |
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0.05% w/w (max) N.F.XIII/0.1% w/w/U.S.P. |
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Chromatographic Purity
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Complies with U.S.P. test. |
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Organic Volatile Impurities |
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Complies with U.S.P. test. |
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Heavy Metals |
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0.001% (U.S.P. limit). |
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Assay |
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98.0% to 102% of C7H7NO2 calculated on the anhydrous basis.
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Description |
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Colourless crystalline powder.
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C7H6O3
(M.W. 138.12)) |
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Odour |
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Almost Odourless. |
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Melting Range
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158.5 0 C to 161.0 0 C. |
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Appearance of Solution/Clarity & Colour of Solution |
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Passes test as per B.P./I.P |
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Heavy Metals |
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20 ppm (max.) |
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Sulphated Ash/Residue on Ignition |
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0.1% w/w (I.P./B.P.Limit) / 0.05%w/w (U.S.P. Limit) |
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Chloride |
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125 ppm (max.) I.P./100 ppm (max.) B.P. |
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Sulphate |
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0.02% (max.) I.P./140 ppm U.S.P. |
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Related Substance |
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Complies with the B.P. test |
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Loss of Drying |
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0.5% (max.) B.P. |
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Iron |
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2 ppm (max.) I.P. |
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Readily Carbonisable Substance |
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Passes test |
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Assay |
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99.0% to 100.5% I.P./B.P., 99.5% to 101% U.S.P. of C7H6O3 with reference to substance
dried over Silica Gel for three hours. |
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Chemical Name |
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O-Hydroxy Benzoic Acid |
C7H6O3
(M.W. 138.12)) |
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Technical Information
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White crystals or nearly white powder in two grades, i.e. Technical Salicylic Acid
and Salicylic Acid IP/BP/USP. Sublimes readily.pH of saturated solution is 2.4
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Solubility
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1 gm dissolves in 460ml of cold water,
15 ml of boiling water, 2.7 ml of alcohol, 3 ml of acetone, 42ml of chloroform,
3ml of ether, 135ml of benzene,
52ml oil turpentine, 60ml of glycerol and 80ml of fats & oil
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Description |
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A crystalline powder of not more than reddish buff colour. |
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Melting Point |
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Not less than 156.5oC |
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Ash |
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0.5% (max) |
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Assay |
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(Total acidity as Salicylic Acid) 98.5% (min)
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Description |
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Colourless Aromatic Liquid having a strong, persistent and characteristic Odour. |
C15H22O3
(M.W. 250.33 g/mol)) |
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Purity (Content of Methyl Salicylate) |
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Minimum 99.0% |
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Refractive Index |
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1.500 to 1.503 |
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Specific Gravity |
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1.011 to 1.016 |
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Acidity |
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0.2 mgKOH/g maximum |
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Uses |
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Its primary use is in sunscreens and other cosmetics to absorb UV-B rays from the
sun, protecting the skin from damage |
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Description |
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Transparent, colorless crystals.. |
C9H8O4
(M.W. 180.157 g/mol)) |
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Purity |
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Minimum 99.5% |
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Refractive Index |
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1.500 to 1.503 |
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Specific Gravity |
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1.40
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Acidity |
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0.2 mgKOH/g maximum |
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Uses |
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Its used for aches and pains for headaches, period pains, toothache, the pain of
bruises and other injuries, and after dental treatment |
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